Paraquat is a restricted use herbicide that was first commercialized in the 1960s and it is found in herbicides such Gramoxone, Helmquat, and Parazone. It is a non-selective, contact herbicide and desiccant that belongs in group 22 site of action(photosystem I electron diverter). Paraquat is one of the most widely applied herbicides in the United States where it is heavily used in corn, cotton, and soybeans and some specialty crops like grapes, peanuts, and pistachios for weed management and crop desiccation. Paraquat has a low oral LD50 and the signal word “Danger” is used on product labels to signify this risk.
The 15-year EPA herbicide registration review for paraquat began in December 2011. In 2016, there were several new safety measures implemented in order to mitigate the of human illness and injury caused by accidental paraquat toxicity. These include:
In August of 2021, the EPA released the final Interim Decision (ID) for paraquat. These EPA determined that these additional label parameters are necessary to mitigate the risk of human illness and injury. The parameters are as follows:
Table 1. The maximum number of applications, annual rates, and single rate application, the minimum retreatment interval, and Pre-Harvest Interval (PHI) for paraquat use in alfalfa, fallow, and wheat (Sourced from the Gramoxone SL 3.0 label).
Crop |
Application Timing |
Max # of application/yr |
Maximum annual rates |
Maximum single application rate |
Minimum retreatment interval |
Pre-Harvest Interval |
Alfalfa |
PRE, PP, Broadcast, or Banded over row in no-till or conventional planting |
2 |
2.7 pts/ac (do not exceed 1.0 lbs ai/ac/year for all paraquat containing products) |
2.7 pts/ac |
7 days |
Harvest at normal maturity |
New seedling (do not use on alfalfa grown for seed) |
1 |
1.3 pt/ac (do not exceed 1. 0 lbs ai/ac/year for all paraquat containing products) |
1.3 pts/ac |
NA |
70 days |
|
Between cuttings in established stand |
3 |
2 pts/ac (do not exceed 0.75 lbs ai in between cuttings applications; do not exceed 1.0 lbs ai/ac/year for all paraquat containing products) |
0.7 pts/ac |
1 application/cutting interval |
30 days for cutting, harvesting, and grazing |
|
Dormant |
1 |
2 pts/ac (do not exceed 0.75 lbs ai for dormant applications; do not exceed 1.0 lbs ai/ac/year for all paraquat containing products) |
2.0 pts/ac |
NA |
42 days in KS, NE, MO, CO for established stands and 60 days in OK for established stands and newly established stands in KS, NE, MO, CO, and OK |
|
Fallow |
2 |
5.4 pts/ac (do not exceed 2.0 lbs ai/ac/year for chemical fallow applications) |
2.7 pts/ac |
7 days |
NA |
|
Wheat |
PRE and PP |
3 |
8.0 pts/ac (do not exceed 3.0 lbs ai/ac/year for PRE and PP applications) |
2.7 pts/ac |
7 days |
Harvest grain, straw, forage, and hay at normal maturity |
Table 2. The maximum number of applications, annual rates, and single rate application, the minimum retreatment interval, and Pre-Harvest Interval (PHI) for paraquat use in corn, soybeans, and sorghum (Sourced from the Gramoxone SL 3.0 label).
Crop |
Application Timing |
Max # of application/yr |
Maximum annual rates |
Maximum single application rate |
Minimum retreatment interval |
Pre-Harvest Interval |
Corn |
PRE and PP |
3 |
8.0 pts/ac (do not exceed 3.0 lbs ai/ac/year for PRE and PP applications; do not exceed 5.0 lbs ai/ac/year for all paraquat containing products) |
2.7 pts/ac |
7 days |
Harvest at normal maturity |
POST directed |
3 |
4.0 pts/ac (do not exceed 1.5 lbs ai/ac/year for POST directed applications; do not exceed 5.0 lbs ai/ac/year for all paraquat containing products) |
1.3 pts/ac |
7 days |
Harvest at normal maturity |
|
Harvest aid |
1 |
1.3 pts/ac (do not exceed 0.5 lbs ai/ac/year for Harvest aid applications; do not exceed 5.0 lbs ai/ac/year for all paraquat containing products) |
1.3 pts/ac |
NA |
7 days for grain and stover |
|
Soybeans |
PRE and PP |
3 |
4.0 pts/ac (do not exceed 1.5 lbs ai/ac/year for PRE and PP applications; do not exceed 2.9 lbs ai/ac/year for all paraquat containing products) |
2.7 pts/ac |
7 days |
Forage/hay: Not before R3 Seed: Harvest at normal maturity |
POST directed |
2 |
1.3 pts/ac (do not exceed 1.0 lbs ai/ac/year for POST applications; do not exceed 2.75 lbs ai/ac/year for all paraquat containing products) |
1.3 pts/ac |
14 days |
Forage/hay: 46 days |
|
Harvest aid |
1 |
0.7 pts/ac (do not exceed 0.25 lbs ai/ac/year for harvest aid applications; do not exceed 2.75 lbs ai/ac/year for all paraquat containing products) |
10.7 fl/oz |
14 days |
Grain only: 15 days Soybeans grown for research, field trials, and seed production only: 3 days |
|
Sorghum |
PRE and PP |
3 |
8.0 pts/ac (do not exceed 3.0 lbs ai/ac/year for PRE and PP applications; do not exceed 4.0 lbs ai/ac/year for all paraquat containing products) |
2.7 pts/ac |
7 days |
Forage: 20 days Grain: 48 days |
POST directed |
2 |
2.7 pts/ac (do not exceed 1.0 lbs ai/ac/year for POST applications; do not exceed 4.0 lbs ai/ac/year for all paraquat containing products) |
2.7 pts/ac |
7 days |
Forage: 20 days Grain: 48 days |
Table 3. The maximum number of applications, annual rates, and single rate application, the minimum retreatment interval, and Pre-Harvest Interval (PHI) for paraquat use in cotton and sunflower (Sourced from the Gramoxone SL 3.0 label).
Crop |
Application Timing |
Max # of application/year |
Maximum annual rates |
Maximum single application rate |
Minimum retreatment interval |
Pre-Harvest Interval |
Cotton |
PRE and PP |
3 |
8.0 pts/ac (do not exceed 3.0 lbs ai/ac/year for PRE and PP applications; do not exceed 3.0 lbs ai/ac/year for all paraquat containing products) |
2.7 pts/ac |
7 days |
Harvest at normal maturity |
POST directed |
3 |
4.0 pts/ac (do not exceed 1.5 lbs ai/ac/year for POST directed applications; do not exceed 3.0 lbs ai/ac/year for all paraquat containing products) |
1.3 pts/ac |
14 days |
Harvest at normal maturity |
|
Harvest aid |
4 |
1.3 pts/ac (do not exceed 0.5 lbs ai/ac/year for Harvest aid applications; do not exceed 3.0 lbs ai/ac/year for all paraquat containing products) |
1.3 pts/ac |
7 days |
7 days for western cotton and 3 days for all other cotton |
|
Sunflower |
PRE and PP |
3 |
8.0 pts/ac (do not exceed 3.0 lbs ai/ac/year for all paraquat containing products) |
2.7 pts/ac |
7 days |
Harvest at normal maturity |
Desiccation |
2 |
1.3 pts/ac (do not exceed 1.0 lbs ai/ac/year for paraquat-containing desiccation products; do not exceed 3.0 lbs ai/ac/year for all paraquat containing products) |
1.3 pts/ac |
7 days |
7 days |
Although the ID is finalized, the paraquat herbicide registration is not complete and will not be completed unto the environmental risk assessment completed. The final ID can be found at https://www.regulations.gov/document/EPA-HQ-OPP-2011-0855-0307.
Links to the aforementioned paraquat products can be found below:
Gramoxone SL 3.0 label – https://www.syngenta-us.com/herbicides/gramoxone-sl-3.0
Parazone 3 SL – https://www.amvac.com/products/parazone-3-sl
Helmquat label – https://us.helmcrop.com/crop-protection/herbicides/helmquat-3sl
The use of trade names is for clarity to readers and does not imply endorsement of a particular product, nor does exclusion imply non-approval. Always consult the herbicide label for the most current use requirements.
Tyler Meyeres, Weed Science Graduate Student
tpmeyeres@ksu.edu
Sarah Lancaster, Weed Management Specialist
slancaster@ksu.edu
Frannie Miller, Pesticide Safety and IPM Coordinator
fmiller@ksu.edu
Tags: label requirements paraquat application training herbicide